Parthenolide Restores Testosterone Biosynthesis After Nanoplastic Exposure by Blocking ROS-Driven NF-κB Nuclear Translocation

Nanoplastics are pervasive contaminants that adversely affect male reproductive function, yet the molecular basis of polystyrene nanoplastic (PS-NP) toxicity in immature testes and effective preventive strategies remain unclear. Here, male mice (postnatal days 22–35, PND 22–35) and TM3 Leydig cells...

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Detalhes bibliográficos

Principais autores:	Peng Zhao, Hao Yan, Runchang Wang, Jie Zhao, Xiangqin Zheng, Dinggang Li, Xitong Guo, Fengming Ji, Chunlan Long, Lianju Shen, Guanghui Wei, Shengde Wu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-10-01
coleção:	Antioxidants
Assuntos:	polystyrene nanoplastics oxidative stress steroidogenesis parthenolide testosterone
Acesso em linha:	https://www.mdpi.com/2076-3921/14/11/1315
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