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Anaplasma phagocytophilum APH0032 is exposed on the cytosolic face of the pathogen-occupied vacuole and co-opts host cell SUMOylation

Anaplasma phagocytophilum, a member of the family Anaplasmataceae and the obligate intracellular bacterium that causes granulocytic anaplasmosis, resides in a host cell-derived vacuole. Bacterial proteins that localize to the A. phagocytophilum-occupied vacuole membrane (AVM) are critical host-patho...

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Principais autores: Aminat T Oki, Bernice Huang, Andrea R Beyer, Levi J May, Hilary K Truchan, Naomi J Walker, Nathan L Galloway, Dori L Borjesson, Jason A Carlyon
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016-09-01
Serier:Frontiers in Cellular and Infection Microbiology
Fag:
Anaplasma
Rickettsia
Sumoylation
Bacterial effector
Pathogen-occupied vacuole
obligate intracellular bacteria
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00108/full
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