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15-LOX metabolites and angiogenesis: angiostatic effect of 15(S)-HPETE involves induction of apoptosis in adipose endothelial cells

Inflammation is critical in the dysregulated growth of adipose tissue and associated vascular dysfunctions. 15-Lipoxygenase metabolites, important mediators of inflammation in adipose tissue during obese conditions, may contribute to codependence of inflammation and angiogenesis in adipose tissue. W...

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Principais autores: Sasikumar J. Soumya, Sheela Binu, Antony Helen, Pallu Reddanna, Perumana R. Sudhakaran
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2014-10-01
Serier:PeerJ
Fag:
Adipose tissue-angiogenesis
15-lipoxygenase
15(S)-HPETE
VEGF
Apoptosis
Online adgang:https://peerj.com/articles/635.pdf
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