Transient receptor potential melastatin 2 regulates neutrophil extracellular traps formation and delays resolution of neutrophil-driven sterile inflammation

Abstract The formation of neutrophil extracellular traps (NETs) is a process releasing into the extracellular space networks of chromatin fibers decorated with granular proteins. It is implicated in infection-related as well as sterile inflammation. Monosodium urate (MSU) crystals serve as damage-as...

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Auteurs principaux:	Xue Cao, Yanhong Li, Yubin Luo, Tianshu Chu, Hang Yang, Ji Wen, Yi Liu, Yi Zhao, Martin Herrmann
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2023-02-01
Collection:	Journal of Inflammation
Sujets:	TRPM2 Neutrophil extracellular traps Sterile inflammation MSU crystals ROS NET formation
Accès en ligne:	https://doi.org/10.1186/s12950-023-00334-1
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