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Trastuzumab Modified Barium Ferrite Magnetic Nanoparticles Labeled with Radium-223: A New Potential Radiobioconjugate for Alpha Radioimmunotherapy

Barium ferrite nanoparticles (BaFeNPs) were investigated as vehicles for <sup>223</sup>Ra radionuclide in targeted α-therapy. BaFe nanoparticles were labeled using a hydrothermal Ba<sup>2+</sup> cations replacement by <sup>223</sup>Ra with yield reaching 61.3 ± 1.8%. Radiolabeled nanoparticles were...

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Principais autores: Weronika Gawęda, Marek Pruszyński, Edyta Cędrowska, Magdalena Rodak, Agnieszka Majkowska-Pilip, Damian Gaweł, Frank Bruchertseifer, Alfred Morgenstern, Aleksander Bilewicz
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-10-01
coleção:Nanomaterials
Assuntos:
alpha radioimmunotherapy
radium-223
barium ferrite
Acesso em linha:https://www.mdpi.com/2079-4991/10/10/2067
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