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Identification of epigenetic modulators as determinants of nuclear size and shape

The shape and size of the human cell nucleus is highly variable among cell types and tissues. Changes in nuclear morphology are associated with disease, including cancer, as well as with premature and normal aging. Despite the very fundamental nature of nuclear morphology, the cellular factors that...

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Principais autores: Andria C Schibler, Predrag Jevtic, Gianluca Pegoraro, Daniel L Levy, Tom Misteli
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications Ltd 2023-05-01
Series:eLife
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Acceso en liña:https://elifesciences.org/articles/80653
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