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A role for Gic1 and Gic2 in Cdc42 polarization at elevated temperature.

The conserved Rho-family GTPase Cdc42 is a master regulator of polarity establishment in many cell types. Cdc42 becomes activated and concentrated in a region of the cell cortex, and recruits a variety of effector proteins to that site. In turn, many effectors participate in regulation of cytoskelet...

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Bibliografische Detailangaben
Hauptverfasser: Christine N Daniels, Trevin R Zyla, Daniel J Lew
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2018-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:https://doi.org/10.1371/journal.pone.0200863
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