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The BtaF Adhesin Is Necessary for Full Virulence During Respiratory Infection by Brucella suis and Is a Novel Immunogen for Nasal Vaccination Against Brucella Infection

Brucella enters their hosts mostly through mucosae from where it spreads systemically. Adhesion to extracellular matrix (ECM) components or to host cells is important for the infectious process, and is mediated by several adhesins, including the BtaF trimeric autotransporter. Although Th1 responses...

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Gespeichert in:
Hauptverfasser: Florencia Muñoz González, Gabriela Sycz, Iván M. Alonso Paiva, Dirk Linke, Angeles Zorreguieta, Pablo C. Baldi, Mariana C. Ferrero
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019-07-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
Brucella suis
bacterial adhesins
BtaF autotransporter
respiratory infection
nasal immunization
mucosal immunity
Online-Zugang:https://www.frontiersin.org/article/10.3389/fimmu.2019.01775/full
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