Rubicon-deficiency sensitizes mice to mixed lineage kinase domain-like (MLKL)-mediated kidney ischemia-reperfusion injury

Abstract The cytosolic protein rubicon (RUBCN) has been implicated in the removal of necrotic debris and autoimmunity. However, the role of RUBCN in models of acute kidney injury (AKI), a condition that typically involves necrotic kidney tubules, was not investigated. Here, we demonstrate that RUBCN...

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Egile Nagusiak:	Wulf Tonnus, Sophie Locke, Claudia Meyer, Francesca Maremonti, Lena Eggert, Anne von Mässenhausen, Stefan R. Bornstein, Douglas R. Green, Andreas Linkermann
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Publishing Group 2022-03-01
Saila:	Cell Death and Disease
Sarrera elektronikoa:	https://doi.org/10.1038/s41419-022-04682-3
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