Peptidyl-prolyl cis/trans isomerase Pin1 interacts with hepatitis B virus core particle, but not with HBc protein, to promote HBV replication

Here, we demonstrate that the peptidyl-prolyl cis/trans isomerase Pin1 interacts noncovalently with the hepatitis B virus (HBV) core particle through phosphorylated serine/threonine-proline (pS/TP) motifs in the carboxyl-terminal domain (CTD) but not with particle-defective, dimer-positive mutants o...

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Hlavní autoři:	Hyeonjoong Kwon, Jumi Kim, Chanho Song, Muhammad Azhar Sajjad, Jiseon Ha, Jaesung Jung, Sun Park, Ho-Joon Shin, Kyongmin Kim
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-06-01
Edice:	Frontiers in Cellular and Infection Microbiology
Témata:	hepatitis B virus HBV replication core particle PPIase Pin1 Pin1-core particle interaction
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fcimb.2023.1195063/full
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