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Health effects of high serum calcium levels: Updated phenome-wide Mendelian randomisation investigation and review of Mendelian randomisation studies

Summary: Background: Calcium plays a role in a wide range of biological functions. Here we conducted a phenome-wide Mendelian randomisation (MR-PheWAS) analysis and a systematic review for MR studies to comprehensively investigate the health effects of serum calcium. Methods: One-hundred and thirty...

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Principais autores: Shuai Yuan, Lili Yu, Wanglong Gou, Lijuan Wang, Jing Sun, Doudou Li, Ying Lu, Xiaxia Cai, Huanling Yu, Changzheng Yuan, Ju-sheng Zheng, Susanna C. Larsson, Evropi Theodoratou, Xue Li
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-02-01
coleção:EBioMedicine
Assuntos:
Calcium
Health
Mendelian randomisation
PheWAS
Systematic review
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352396422000494
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