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Microbiological diagnosis of pleural infections: a comparative evaluation of a novel syndromic real-time PCR panel

ABSTRACT Current microbial diagnostics for pleural infections are insufficient. Studies using 16S targeted next-generation sequencing report that only 10%–16% of bacteria present are cultured and that 50%–78% of pleural fluids containing relevant microbial DNA remain culture negative. As a rapid dia...

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Автори: Øyvind Kommedal, Tomas Mikal Eagan, Øystein Fløtten, Truls Michael Leegaard, William Siljan, Hilde Fardal, Bjørnar Bø, Fredrik Grøvan, Kjersti Wik Larssen, Arne Kildahl-Andersen, Reidar Hjetland, Rune Tilseth, Sølvi Kristine Øyen Hareide, Marit Tellevik, Ruben Dyrhovden
Формат: Artigo
Мова:Inglês
Опубліковано: American Society for Microbiology 2024-06-01
Серія:Microbiology Spectrum
Предмети:
pleural infection
pleural empyema
syndromic PCR
diagnostics
Fusobacterium nucleatum
Streptococcus intermedius
Онлайн доступ:https://journals.asm.org/doi/10.1128/spectrum.03510-23
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