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New Pyrazolo-Benzimidazole Mannich Bases with Antimicrobial and Antibiofilm Activities

A new series of pyrazolo-benzimidazole hybrid Mannich bases were synthesized, characterized by <sup>1</sup>H-NMR, <sup>13</sup>C-NMR, IR, UV-Vis, MS, and elemental analysis. In vitro cytotoxicity of the new compounds studied on fibroblast cells showed that the newly synthesized pyrazolo-benzimidazol...

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Principais autores: Christina Zalaru, Florea Dumitrascu, Constantin Draghici, Isabela Tarcomnicu, Maria Marinescu, George Mihai Nitulescu, Rodica Tatia, Lucia Moldovan, Marcela Popa, Mariana Carmen Chifiriuc
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-08-01
Serier:Antibiotics
Fag:
pyrazoles
benzimidazoles
hybrid heterocyclic molecules
cytotoxicity
antimicrobial
biofilm formation
Online adgang:https://www.mdpi.com/2079-6382/11/8/1094
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