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Treatment of pancreatic cancer with irreversible electroporation and intratumoral CD40 antibody stimulates systemic immune responses that inhibit liver metastasis in an orthotopic model

Background Pancreatic cancer (PC) has a poor prognosis, and most patients present with either locally advanced or distant metastatic disease. Irreversible electroporation (IRE) is a non-thermal method of ablation used clinically in locally advanced PC, but most patients eventually develop distant re...

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Bibliografische Detailangaben
Hauptverfasser: Partha Ray, Tomoko Hayashi, Karen Messer, Stephen Schoenberger, Aaron Miller, Dennis Carson, Sara McArdle, Zbigniew Mikulski, Jayanth S Shankara Narayanan, Suna Erdem, Herve Tiriac, Minya Pu, Rebekah R White
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2023-01-01
Schriftenreihe:Journal for ImmunoTherapy of Cancer
Online-Zugang:https://jitc.bmj.com/content/11/1/e006133.full
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