Tris-hydroxymethyl-aminomethane enhances capsaicin-induced intracellular Ca2+ influx through transient receptor potential V1 (TRPV1) channels

Non-selective transient receptor potential vanilloid (TRPV) cation channels are activated by various insults, including exposure to heat, acidity, and the compound capsaicin, resulting in sensations of pain in the skin, visceral organs, and oral cavity. Recently, TRPV1 activation was also demonstrat...

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Detalhes bibliográficos

Principais autores:	Satoshi Murakami, Yuka Sudo, Kanako Miyano, Hitomi Nishimura, Motohiro Matoba, Seiji Shiraishi, Hiroki Konno, Yasuhito Uezono
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2016-02-01
coleção:	Journal of Pharmacological Sciences
Assuntos:	Calcium signaling Nociceptive pain Tris-hydroxymethyl aminomethane (THAM) TRPV cation channels TRPV1 receptor
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S1347861315002315
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