In Situ Gel Formation in Microporated Skin for Enhanced Topical Delivery of Niacinamide

Although used widely in cosmetic formulations, topical delivery of niacinamide (LogP = −0.35) is unfavorable by conventional means. Poly(lactide-<i>co</i>-glycolide) (PLGA) formulations, can undergo a sol-gel transition triggered by solvent exchange, entrapping molecules and sustaining their release...

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Principais autores:	Sonalika Bhattaccharjee, Moritz Beck-Broichsitter, Ajay K. Banga
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2020-05-01
Serija:	Pharmaceutics
Teme:	Microneedle Poly(lactide-<i>co</i>-glycolide) In situ gel In vitro permeation testing Topical drug delivery
Online dostop:	https://www.mdpi.com/1999-4923/12/5/472
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