The PP2A phosphatase counteracts the function of the 9-1-1 axis in checkpoint activation
Summary: DNA damage elicits a checkpoint response depending on the Mec1/ATR kinase, which detects the presence of single-stranded DNA and activates the effector kinase Rad53/CHK2. In Saccharomyces cerevisiae, one of the signaling circuits leading to Rad53 activation involves the evolutionarily conse...
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| Principais autores: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2023-11-01
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| 叢編: | Cell Reports |
| 主題: | |
| 在線閱讀: | http://www.sciencedirect.com/science/article/pii/S2211124723013724 |
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