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Metabolic engineering of Pseudomonas putida KT2440 to produce anthranilate from glucose

The Pseudomonas putida KT2440 strain was engineered in order to produce anthranilate (oAB, ortho-aminobenzoate), a precursor of the aromatic amino acid tryptophan, from glucose as sole carbon source. To enable the production of the metabolic intermediate oAB, the trpDC operon encoding an anthranilat...

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Principais autores: Jannis eKuepper, Jasmin eDickler, Michael eBiggel, Swantje eBehnken, Gernot eJaeger, Nick eWierckx, Lars M Blank
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015-11-01
coleção:Frontiers in Microbiology
Assuntos:
Metabolic Engineering
Industrial Biotechnology
Anthranilic acid
Pseudomonas putida KT2440
Aromatic amino acid pathway
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01310/full
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