HAMLET binding to α-actinin facilitates tumor cell detachment.
Cell adhesion is tightly regulated by specific molecular interactions and detachment from the extracellular matrix modifies proliferation and survival. HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) is a protein-lipid complex with tumoricidal activity that also triggers tumor cell detac...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science (PLoS)
2011-03-01
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| Edice: | PLoS ONE |
| On-line přístup: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21408150/?tool=EBI |
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