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Inflammation can increase hepcidin in HFE‐hereditary hemochromatosis

Abstract We present a p.C282Y homozygous patient with high hepcidin levels and normal iron parameters during systemic inflammation. This suggests that in the absence of a proper functioning HFE, resulting in blockage of the BMP/SMAD pathway, the innate low hepcidin concentration can be upregulated b...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Wenke Moris, Pauline L. M. Verhaegh, Ad A. M. Masclee, Dorine W. Swinkels, Coby M. Laarakkers, Ger H. Koek, Cees Th. B. M. vanDeursen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2021-05-01
Schriftenreihe:Clinical Case Reports
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Online-Zugang:https://doi.org/10.1002/ccr3.4114
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