Circulating immunoglobulins and transient lymphocytopenia in a sub-study of CAPRISA 012B, testing HIV monoclonal antibodies in a phase 1 trial

Abstract Acute, transient lymphocytopenia, not clinically significant was observed in the CAPRISA 012B phase 1 clinical trial following administration of broadly neutralizing antibodies (bnAb)-CAP256V2LS alone or with VRC07-523LS. Lymphocytopenia was assigned upon a > 50% decline in absolute lymphoc...

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Hlavní autoři:	Parveen Sobia, Sharana Mahomed, Aida Sivro, Stephane Paul, Farzana Osman, Ishana Harkoo, Nigel Garrett, Quarraisha Abdool Karim, Salim S. Abdool Karim, Derseree Archary
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-06-01
Edice:	Scientific Reports
On-line přístup:	https://doi.org/10.1038/s41598-024-63902-2
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