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Structural Perspectives of Insulin Receptor Isoform-Selective Insulin Analogs

A significant drawback of the exogenous administration of insulin to diabetics is the non-physiological profile of insulin action resulting in the insufficient suppression of hepatic glucose production, which is the main contributing factor to diabetic hyperglycemia under fasting conditions and the...

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Bibliographic Details
Main Authors: Jiří Jiráček, Lenka Žáková
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00167/full
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