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Acetoacetate, a ketone body, attenuates neuronal bursts in acutely-induced epileptiform slices of the mouse hippocampus

The ketogenic diet increases ketone bodies (β-hydroxybutyrate and acetoacetate) in the brain, and ameliorates epileptic seizures in vivo. However, ketone bodies exert weak or no effects on electrical activity in rodent hippocampal slices. Especially, it remains unclear what kinds of conditions are r...

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Bibliografiske detaljer
Principais autores: Hao Wen, Nagisa Sada, Tsuyoshi Inoue
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-03-01
Serier:Frontiers in Cellular Neuroscience
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fncel.2025.1551700/full
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