Risk Allele rs117026326-Mediated Alternative Splicing of GTF2I Promotes B Cell Proliferation in Primary Sjögren’s Syndrome
Conclusion: pSS risk allele of rs117026326 modulates alternative splicing of GTF2I and upregulates GTF2IΔ isoform, which promotes B cell proliferation through enhancing binding and transcription of c-FOS.
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Wiley
2025-01-01
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| Seria: | Journal of Immunology Research |
| Dostęp online: | http://dx.doi.org/10.1155/jimr/4821639 |
| Etykiety: |
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