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Eucommia ulmoides cortex, geniposide and aucubin regulate lipotoxicity through the inhibition of lysosomal BAX.

In this study we examined the inhibition of hepatic dyslipidemia by Eucommia ulmoides extract (EUE). Using a screening assay for BAX inhibition we determined that EUE regulates BAX-induced cell death. Among various cell death stimuli tested EUE regulated palmitate-induced cell death, which involves...

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Hlavní autoři: Geum-Hwa Lee, Mi-Rin Lee, Hwa-Young Lee, Seung Hyun Kim, Hye-Kyung Kim, Hyung-Ryong Kim, Han-Jung Chae
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2014-01-01
Edice:PLoS ONE
On-line přístup:https://doi.org/10.1371/journal.pone.0088017
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