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Lupeol as a Potential Inhibitor of NorA Efflux Pumps in Staphylococcus aureus: In Silico and In Vitro Evidence

Antimicrobial resistance remains one of the major challenges to global public health, compromising the effectiveness of treatments and contributing to increased morbidity and mortality associated with bacterial infections. Among the mechanisms involved, efflux pumps—such as NorA, expressed in resist...

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Tallennettuna:
Päätekijät: Nara Juliana Santos Araújo, Camila Aparecida Pereira Silva, Vanessa Lima Bezerra, Cicera Datiane Morais Oliveira‐Tintino, Gabriel Gonçalves de Alencar, Maria do Socorro Costa, Ana Raquel Pereira da Silva, Josefa Sayonara dos Santos, Kamila Correa Camara, Heberty diTarso Fernandes Facundo, Lívia Pereira Ferreira, Henrique Douglas Melo Coutinho, José Maria Barbosa Filho, Carolina Bandeira Domiciano, José Bezerra de Araújo‐Neto, Jacqueline Cosmo Andrade‐Pinheiro
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Wiley-VCH 2025-11-01
Sarja:ChemistryOpen
Aiheet:
docking moleculars
emissão fluorescência
NorA
permeabilidade de membranes
Staphylococcus aureus
Linkit:https://doi.org/10.1002/open.202500227
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