Packed Bed Bioreactor for the Isolation and Expansion of Placental-Derived Mesenchymal Stromal Cells.

Large numbers of Mesenchymal stem/stromal cells (MSCs) are required for clinical relevant doses to treat a number of diseases. To economically manufacture these MSCs, an automated bioreactor system will be required. Herein we describe the development of a scalable closed-system, packed bed bioreacto...

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Autors principals:	Michael J Osiecki, Thomas D Michl, Betul Kul Babur, Mahboubeh Kabiri, Kerry Atkinson, William B Lott, Hans J Griesser, Michael R Doran
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2015-01-01
Col·lecció:	PLoS ONE
Accés en línia:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0144941&type=printable
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