Computational exploration of molecular flexibility and interaction of meropenem analogs with the active site of oxacillinase-23 in Acinetobacter baumannii

Background: Carbapenem-resistant Acinetobacter baumannii is an opportunistic pathogen responsible for nosocomial infections and is one of the biggest global threats according to the World Health Organization (WHO), particularly causing substantial morbidity and mortality.Objectives: This study aimed...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Balajee Ramachandran, Saravanan Muthupandian, Jeyakanthan Jeyaraman, Bruno Silvester Lopes
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-02-01
Colecção:	Frontiers in Chemistry
Assuntos:	Acinetobacter baumannii beta-lactamases oxacillinase OXA-23 OXA-23 variants meropenem
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fchem.2023.1090630/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!