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Convergent alterations in the tumor microenvironment of MYC-driven human and murine prostate cancer

Abstract How prostate cancer cells and their precursors mediate changes in the tumor microenvironment (TME) to drive prostate cancer progression is unclear, in part due to the inability to longitudinally study the disease evolution in human tissues. To overcome this limitation, we perform extensive...

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Autori principali: Mindy K. Graham, Rulin Wang, Roshan Chikarmane, Bulouere Abel, Ajay Vaghasia, Anuj Gupta, Qizhi Zheng, Jessica Hicks, Polina Sysa-Shah, Xin Pan, Nicole Castagna, Jianyong Liu, Jennifer Meyers, Alyza Skaist, Yan Zhang, Michael Rubenstein, Kornel Schuebel, Brian W. Simons, Charles J. Bieberich, William G. Nelson, Shawn E. Lupold, Theodore L. DeWeese, Angelo M. De Marzo, Srinivasan Yegnasubramanian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2024-08-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-024-51450-2
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