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Immunization with GP1 but Not Core-like Particles Displaying Isolated Receptor-Binding Epitopes Elicits Virus-Neutralizing Antibodies against Junín Virus

New World arenaviruses are rodent-transmitted viruses and include a number of pathogens that are responsible for causing severe human disease. This includes Junín virus (JUNV), which is the causative agent of Argentine hemorrhagic fever. The wild nature and mobility of the rodent reservoir host make...

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Uloženo v:
Hlavní autoři: Gleyder Roman-Sosa, Anne Leske, Xenia Ficht, Tung Huy Dau, Julia Holzerland, Thomas Hoenen, Martin Beer, Robert Kammerer, Reinhold Schirmbeck, Felix A. Rey, Sandra M. Cordo, Allison Groseth
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2022-01-01
Edice:Vaccines
Témata:
arenavirus
Junín virus
immune response
neutralizing antibodies
glycoprotein
GP1
On-line přístup:https://www.mdpi.com/2076-393X/10/2/173
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