MicroRNA-139 inhibits hepatocellular carcinoma cell growth through down-regulating karyopherin alpha 2

Abstract Background MicroRNA-139-5p (miR-139) has been shown to play important roles in hepatocellular carcinoma (HCC) development. However, the exact mechanism of miR-139 in HCC remains largely unknown. Methods We investigated the function in human cell lines and patient tissue samples by experimen...

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Detalhes bibliográficos

Principais autores:	Ying Zan, Baofeng Wang, Liang Liang, Yujiao Deng, Tian Tian, Zhijun Dai, Lei Dong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2019-05-01
coleção:	Journal of Experimental & Clinical Cancer Research
Assuntos:	Survival Epithelial-to-mesenchymal transition Colony formation Migration and invasion
Acesso em linha:	http://link.springer.com/article/10.1186/s13046-019-1175-2
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