Resorufin analogs preferentially bind cerebrovascular amyloid: potential use as imaging ligands for cerebral amyloid angiopathy

<p>Abstract</p> <p>Background</p> <p>Cerebral amyloid angiopathy (CAA) is characterized by deposition of fibrillar amyloid β (Aβ) within cerebral vessels. It is commonly seen in the elderly and almost universally present in patients with Alzheimer's Disease (AD). In both patient populations, CAA is...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Han Byung, Zhou Meng-liang, Vellimana Ananth K, Milner Eric, Kim David H, Greenberg Jacob K, Chu Wenhua, Mach Robert H, Zipfel Gregory J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2011-12-01
coleção:	Molecular Neurodegeneration
Assuntos:	Cerebral amyloid angiopathy Alzheimer's disease dementia diagnosis amyloid beta positron emission tomography amyloid imaging tracer resorufin phenoxazines
Acesso em linha:	http://www.molecularneurodegeneration.com/content/6/1/86
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!