Choosing the most suitable NGS technology to combine with a standardized viral enrichment protocol for obtaining complete avian orthoreovirus genomes from metagenomic samples

Since viruses are obligate intracellular pathogens, sequencing their genomes results in metagenomic data from both the virus and the host. Virology researchers are constantly seeking new, cost-effective strategies and bioinformatic pipelines for the retrieval of complete viral genomes from these met...

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Principais autores:	Sonsiray Álvarez-Narváez, Telvin L. Harrell, Islam Nour, Sujit K. Mohanty, Steven J. Conrad
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-02-01
Colecção:	Frontiers in Bioinformatics
Assuntos:	avian orthoreovirus ARV whole genome sequencing WGS short-read sequencing long-read sequencing
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fbinf.2025.1498921/full
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