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Genomic surveillance reveals a dengue 2 virus epidemic lineage with a marked decrease in sensitivity to Mosnodenvir

Abstract Dengue fever is the most important arbovirosis for public health, with more than 5 million cases worldwide in 2023. Mosnodenvir is the first anti-dengue compound with very high preclinical pan-serotype activity, currently undergoing phase 2 clinical evaluation. Here, by analyzing dengue vir...

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Autors principals: Hawa Sophia Bouzidi, Selin Sen, Géraldine Piorkowski, Laura Pezzi, Nazli Ayhan, Albin Fontaine, Thomas Canivez, Manon Geulen, Rayane Amaral, Gilda Grard, Guillaume André Durand, Xavier de Lamballerie, Franck Touret, Raphaëlle Klitting
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2024-10-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/s41467-024-52819-z
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