AcrIIA7 hijacks tracrRNA to block CRISPR-Cas system
Abstract The CRISPR–Cas9 system provides adaptive immunity against invading genetic elements through a dual-RNA-guided DNA cleavage mechanism. This system relies on the precise assembly of a ribonucleoprotein (RNP) complex composed of the Cas9 endonuclease, a CRISPR-derived RNA (crRNA), and a trans-...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2026-03-01
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| Series: | Nature Communications |
| Acceso en liña: | https://doi.org/10.1038/s41467-026-70749-w |
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