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Microvascular cerebral blood flow response to intrathecal nicardipine is associated with delayed cerebral ischemia

One of the common complications of non-traumatic subarachnoid hemorrhage (SAH) is delayed cerebral ischemia (DCI). Intrathecal (IT) administration of nicardipine, a calcium channel blocker (CCB), upon detection of large-artery cerebral vasospasm holds promise as a treatment that reduces the incidenc...

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Principais autores: Eashani Sathialingam, Kyle R. Cowdrick, Amanda Y. Liew, Zhou Fang, Seung Yup Lee, Courtney E. McCracken, Feras Akbik, Owen B. Samuels, Prem Kandiah, Ofer Sadan, Erin M. Buckley
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-03-01
Serier:Frontiers in Neurology
Fag:
vasospasm
diffuse correlation spectroscopy
nicardipine
blood flow
subarachnoid hemorrhage
Online adgang:https://www.frontiersin.org/articles/10.3389/fneur.2023.1052232/full
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