Formulation and in vitro evaluation of topical nanosponge-based gel containing butenafine for the treatment of fungal skin infection

In the current study, four formulae (BNS1-BNS4) of butenafine (BTF) loaded nanosponges (NS) were fabricated by solvent emulsification technology, using different concentration of ethyl cellulose (EC) and polyvinyl alcohol (PVA) as a rate retarding polymer and surfactant, respectively. Prepared NS we...

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Main Authors: Mohammed Muqtader Ahmed, Farhat Fatima, Md. Khalid Anwer, Elmutasim Osman Ibnouf, Mohd Abul Kalam, Aws Alshamsan, Mohammed F. Aldawsari, Ahmed Alalaiwe, Mohammad Javed Ansari
Formato: Artigo
Idioma:Inglês
Publicado: Springer 2021-05-01
Series:Saudi Pharmaceutical Journal
Assuntos:
Nanosponges
Topical gel
In-vitro diffusion
Antifungal study
Flux
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S1319016421000670
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