Remimazolam alleviates blood-brain barrier damage by regulating the PI3K/AKT signaling pathway in sepsis-associated encephalopathy mice

Sepsis-associated encephalopathy (SAE) is a common neurological complication in critically ill patients. However, therapeutic strategies for SAE remain limited. Increasing evidence suggests that impairment of the blood-brain barrier (BBB) plays a crucial role in the progression of SAE. Remimazolam h...

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Detalhes bibliográficos

Principais autores:	Bingyan Xu, Xiaoming Wang, Siyu Liu, Yanhuan Guo, Qinghui Dong, Yujia Tao, Min Zhang, Pengfei Ni, Yanhu Xie
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-04-01
Colecção:	Brain Research Bulletin
Assuntos:	Sepsis-associated encephalopathy Blood-brain barrier Remimazolam Lipopolysaccharide Neuroinflammation
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0361923026001103
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