Molecular requirements for peroxisomal targeting of alanine-glyoxylate aminotransferase as an essential determinant in primary hyperoxaluria type 1.

Alanine-glyoxylate aminotransferase is a peroxisomal enzyme, of which various missense mutations lead to irreversible kidney damage via primary hyperoxaluria type 1, in part caused by improper peroxisomal targeting. To unravel the molecular mechanism of its recognition by the peroxisomal receptor Pe...

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Автори:	Krisztián Fodor, Janina Wolf, Ralf Erdmann, Wolfgang Schliebs, Matthias Wilmanns
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Public Library of Science (PLoS) 2012-01-01
Серія:	PLoS Biology
Онлайн доступ:	http://europepmc.org/articles/PMC3328432?pdf=render
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