Role of HLA-I Structural Variants and the Polyreactive Antibodies They Generate in Immune Homeostasis
Cell-surface HLA-I molecules consisting of β2-microglobulin (β2m) associated heavy chains (HCs), referred to as Face-1, primarily present peptides to CD8+ T-cells. HCs consist of three α-domains, with selected amino acid sequences shared by all alleles of all six isoforms. The cell-surface HLA under...
Guardado en:
| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI AG
2022-09-01
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| Colección: | Antibodies |
| Materias: | |
| Acceso en línea: | https://www.mdpi.com/2073-4468/11/3/58 |
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