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Screening of potential oxidative stress-related biomarkers and therapeutic drugs in rheumatoid arthritis based on integrative bioinformatics, machine learning, and molecular dynamics simulations

BackgroundRheumatoid arthritis (RA) is a prevalent autoimmune condition. Increasing evidence reveals that oxidative stress exerts an important effect in the pathogenesis of RA. This research aimed to systematically screen oxidative stress-related biomarkers for RA and further examine promising thera...

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Principais autores: Zhigang Shi, Wenzhuo Qi, Juyin Xue, Shuxu Zhang, Zhou Mu, He Wang, Bingrui Zhu, Peng Kong, Yingguang Han
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-03-01
coleção:Frontiers in Molecular Biosciences
Assuntos:
biomarkers
machine learning
molecular dynamics simulation
oxidative stress
rheumatoid arthritis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmolb.2026.1804435/full
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