Clinical utility of neurofilament light chain as a biomarker for disease onset and progression in hereditary transthyretin amyloidosis

BackgroundNeurofilament light chain levels (NfL) have emerged as a biomarker for early diagnosis and follow-up of hereditary transthyretin variant amyloidosis (ATTRv). We evaluated the most accurate technique for NfL quantifying in ATTRv healthy carriers and symptomatic patients in real-life practic...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Álvaro Gragera-Martínez, Cristina Borrachero Garro, Francisco Muñoz Beamud, Ana Manovel Sánchez, Andrés González Macías, Mariano Pizarro Sánchez, Amelia Jiménez Heffernan, Ana Serrano Mira, Beatriz Macías Dominguez, Sandra Garcia Garrido
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-10-01
Schriftenreihe:	Frontiers in Neurology
Schlagworte:	neurofilament ELISA SiMoA transthyretin amyloidosis ATTRv
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fneur.2025.1660344/full
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