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Effect of lymphotoxin blockage on different stages of Sjogren's syndrome in an animal model

Abstract Background Lymphotoxin (LT) is an important mediator in Sjogren's syndrome (SS), both in patients and in animal models. Deletion of the LT alpha gene prevented the development of disease manifestations in the interelukin alpha transgenic mouse (IL14αTG) mouse model of SS. Aims The current s...

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Auteurs principaux: Alexander Jacob, Long Shen, Jing He, Kelly Nealon, Jessy J. Alexander, Julian L. Ambrus
Format: Artigo
Langue:Inglês
Publié: Wiley 2022-06-01
Collection:Rheumatology & Autoimmunity
Sujets:
Accès en ligne:https://doi.org/10.1002/rai2.12041
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