Immunosuppressive tumor microenvironment and advance in immunotherapy in melanoma bone metastasis

Melanoma frequently develops bone metastases, leading to skeletal-related events and poor survival. The tumor microenvironment (TME) plays a pivotal role in melanoma progression, bone metastasis, and immunotherapy resistance. Key immunosuppressive cells including myeloid-derived suppressor cells (MD...

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Váldodahkkit:	Yiqun Ma, Lin Zhang, Weimin Liu
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2025-08-01
Ráidu:	Frontiers in Immunology
Fáttát:	melanoma bone metastasis osteoclasts tumor microenvironment immune checkpoint inhibitors immunotherapy
Liŋkkat:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1608215/full
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