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Single-Cell Transcriptomic Dataset of RPGR-associated Retinitis Pigmentosa Patient-Derived Retinal Organoids

Abstract X-linked retinitis pigmentosa (XLRP) is a severe hereditary retinal disorder marked by progressive vision loss due to photoreceptor dysfunction. The retinitis pigmentosa GTPase regulator (RPGR) gene, responsible for most XLRP cases, encodes a protein crucial for the transport of visual sign...

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Principais autores: Ting Li, Yuting Ma, Yun Cheng, Yingke Zhao, Zhixu Qiu, Hongli Liu, Daowei Zhang, Jiawen Wu, Junfeng Li, Shenghai Zhang, Jihong Wu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2024-11-01
Serier:Scientific Data
Online adgang:https://doi.org/10.1038/s41597-024-04124-z
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