HIV-1 Nucleocapsid Protein Binds Double-Stranded DNA in Multiple Modes to Regulate Compaction and Capsid Uncoating

The HIV-1 nucleocapsid protein (NC) is a multi-functional protein necessary for viral replication. Recent studies have demonstrated reverse transcription occurs inside the fully intact viral capsid and that the timing of reverse transcription and uncoating are correlated. How a nearly 10 kbp viral D...

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Principais autores:	Helena Gien, Michael Morse, Micah J. McCauley, Jonathan P. Kitzrow, Karin Musier-Forsyth, Robert J. Gorelick, Ioulia Rouzina, Mark C. Williams
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2022-01-01
Series:	Viruses
Assuntos:	DNA condensation optical tweezers atomic force microscopy capsid uncoating HIV-1 nucleocapsid protein
Acceso en liña:	https://www.mdpi.com/1999-4915/14/2/235
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