New insights into the pro-oxidant mechanism of dehydroleucodine on Trypanosoma cruzi

Abstract Chagas disease, caused by Trypanosoma cruzi (T. cruzi), is one of the most important neglected diseases in Latin America. The limited use of the current nitro-derivative-based chemotherapy highlights the need for alternative drugs and the identification of their molecular targets. In this s...

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Bibliografske podrobnosti

Principais autores:	Jessica Gomez, Mauro Coll, Carla Guarise, Diego Cifuente, Diego Masone, Paula Faral- Tello, María Dolores Piñeyro, Carlos Robello, Guillermo Reta, Miguel Ángel Sosa, Patricia Barrera
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2024-08-01
Serija:	Scientific Reports
Teme:	Antiparasitic drug Natural compound Sesquiterpene lactone Trypanosoma cruzi Oxidative stress
Online dostop:	https://doi.org/10.1038/s41598-024-69201-0
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