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Enantioselective recognition of metaclazepam enantiomers by cyclodextrins studied using capillary electrophoresis, NMR spectroscopy and molecular modeling

In the present study, an attempt was made to explain enantioselective noncovalent interactions of metaclazepam (MCZ) enantiomers with three native cyclodextrins (CDs) with different cavity size by combined use of capillary electrophoresis (CE), nuclear magnetic resonance (NMR) spectroscopy and quant...

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Principais autores: Ketevan Museridze, Ann Gogolashvili, Lali Chankvetadze, Vazha Tkemaladze, Giorgi Jibuti, Antonio Salgado, George Jaiani, Roberto Dallocchio, Paola Peluso, Bezhan Chankvetadze
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-05-01
Serier:Journal of Chromatography Open
Fag:
Capillary electrophoresis
Molecular modelling
Enantiomer separation
Separation mechanisms
Online adgang:http://www.sciencedirect.com/science/article/pii/S2772391726000277
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