Clinicopathologic significance of nuclear HER4 and phospho-YAP(S) in human breast cancers and matching brain metastases

Background: Human epidermal growth factor receptor-4 (HER4) and yes-associated protein-1 (YAP) are candidate therapeutic targets in oncology. YAP’s transcriptional coactivation function is modulated by the HER4 intracellular domain (HER4-ICD) in vitro , but the clinical relevance of this has not bee...

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Detalhes bibliográficos

Principais autores:	Priyakshi Kalita-de Croft, Malcolm Lim, Haarika Chittoory, Xavier M. de Luca, Jamie R. Kutasovic, Bryan W. Day, Fares Al-Ejeh, Peter T. Simpson, Amy E. McCart Reed, Sunil R. Lakhani, Jodi M. Saunus
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SAGE Publishing 2020-07-01
coleção:	Therapeutic Advances in Medical Oncology
Acesso em linha:	https://doi.org/10.1177/1758835920946259
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