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Case Report: Pediatric Philadelphia chromosome-positive T-lymphoblastic leukemia relapsing as chronic-phase CML after treatment discontinuation

BackgroundPhiladelphia chromosome (Ph)-positive T-lymphoblastic leukemia (T-ALL) is exceptionally rare. Distinguishing de novo Ph-positive T-ALL from T-lymphoid blast-phase chronic myeloid leukemia (BP-CML) can be highly challenging, yet this distinction has important therapeutic and prognostic impl...

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Principais autores: Rongrong Dong, Xinying Dai, Yuan Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-07-01
coleção:Frontiers in Oncology
Assuntos:
BCR::ABL1
blast phase
chronic myeloid leukemia
Philadelphia chromosome
T-lymphoblastic leukemia
treatment adherence
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2026.1874606/full
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